Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

Conscious dogs undergoing a 15-min coronary occlusion were given alpha-phenyl N-tert-butyl nitrone (PBN) and the local coronary venous plasma was analyzed by electron paramagnetic resonance spectroscopy. A prolonged myocardial release of PBN radical adducts was observed, which exhibited a burst in t...

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Publié dans:	J Clin Invest
Auteurs principaux:	Li, X Y, McCay, P B, Zughaib, M, Jeroudi, M O, Triana, J F, Bolli, R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394382/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116608
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