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Theoretical Considerations on the Topological Organization of Receptor Mosaics

The concept of Receptor Mosaic (RM) is discussed; hence the integrative functions of the assemblage of G-protein coupled receptors physically interacting in the plane of the plasma membrane. The main focus is on a heterotrimer of G-protein coupled receptors, namely the A2A-D2-CB1 receptor trimer. A...

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Bibliographic Details
Main Authors: Agnati, Luigi Francesco, Fuxe, Kjell, Woods, Amina S., Genedani, Susanna, Guidolin, Diego
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949285/
https://ncbi.nlm.nih.gov/pubmed/19751189
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