Impact of arginase II on CBF in experimental cortical impact injury in mice using MRI

Traumatic brain injury (TBI) results in reduced cerebral blood flow (CBF) and low levels of the vasodilator nitric oxide (NO) may be involved. Arginase II negatively regulates NO production through competition for the substrate -arginine. We determined whether arginase II-deficient (ArgII(−/−)) mice...

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Main Authors: Bitner, Brittany R, Brink, Danielle C, Mathew, Leela C, Pautler, Robia G, Robertson, Claudia S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2010
Ábhair:
Brief Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949199/
https://ncbi.nlm.nih.gov/pubmed/20372170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.47
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