Neuronal estrogen receptor-α mediates neuroprotection by 17β-estradiol

17β-Estradiol (E(2)) was shown to exert neuroprotective effects both in in vitro and in vivo models of stroke. Although these effects of E(2) are known to require estrogen receptor-α (ERα), the cellular target of estrogen-mediated neuroprotection remains unknown. Using cell type-specific ER mutant m...

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Autors principals: Elzer, Joachim G, Muhammad, Sajjad, Wintermantel, Tim M, Regnier-Vigouroux, Anne, Ludwig, Jochen, Schütz, Günther, Schwaninger, Markus
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949189/
https://ncbi.nlm.nih.gov/pubmed/20010956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.258
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