Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia

Heat shock protein 27 (HSP27) has a major role in mediating survival responses to a range of central nervous system insults, functioning as a protein chaperone, an antioxidant, and through inhibition of cell death pathways. We have used transgenic mice overexpressing HSP27 (HSP27tg) to examine the r...

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Hlavní autoři: van der Weerd, Louise, Tariq Akbar, Mohammed, Aron Badin, Romina, Valentim, Lauren M, Thomas, David L, Wells, Dominic J, Latchman, David S, Gadian, David G, Lythgoe, Mark F, de Belleroche, Jackie S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949174/
https://ncbi.nlm.nih.gov/pubmed/19997117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.249
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