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Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice

Glial scarring is traditionally thought to be detrimental after stroke. But emerging studies now suggest that reactive astrocytes may also contribute to neurovascular remodeling. Here, we assessed the effects and mechanisms of metabolic inhibition of reactive astrocytes in a mouse model of stroke re...

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Detalhes bibliográficos
Main Authors: Hayakawa, Kazuhide, Nakano, Takafumi, Irie, Keiichi, Higuchi, Sei, Fujioka, Masayuki, Orito, Kensuke, Iwasaki, Katsunori, Jin, Guang, Lo, Eng H, Mishima, Kenichi, Fujiwara, Michihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949171/
https://ncbi.nlm.nih.gov/pubmed/19997116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.257
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