Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation.

A chronic relapsing form of experimental autoimmune encephalomyelitis (CR-EAE) was induced in SJL/J mice by adoptive transfer of lymph node cells (LNC) sensitized to guinea pig myelin basic protein (GMBP). We examined the efficacy of high dose immunosuppressive regimens (cyclophosphamide [CY] 300 mg...

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Detalhes bibliográficos
Main Authors: Karussis, D M, Vourka-Karussis, U, Lehmann, D, Ovadia, H, Mizrachi-Koll, R, Ben-Nun, A, Abramsky, O, Slavin, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC294912/
https://ncbi.nlm.nih.gov/pubmed/7688762
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