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Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest

The mechanisms leading to delayed neuronal death after asphyxial cardiac arrest (ACA) in the developing brain are unknown. This study aimed at investigating the possible role of microglial activation in neuronal death in developing brain after ACA. Postnatal day-17 rats were subjected to 9 mins of A...

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Detalhes bibliográficos
Main Authors: Tang, Minke, Alexander, Henry, Clark, Robert S B, Kochanek, Patrick M, Kagan, Valerian E, Bayır, Hülya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949095/
https://ncbi.nlm.nih.gov/pubmed/19756023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.194
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