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Suppression of growth hormone (GH) secretion by a selective GH-releasing hormone (GHRH) antagonist. Direct evidence for involvement of endogenous GHRH in the generation of GH pulses.

To study the potential involvement of growth hormone-releasing hormone (GHRH) in the generation of growth hormone (GH) pulses in humans we have used a competitive antagonist to the GHRH receptor, (N-Ac-Tyr1,D-Arg2)GHRH(1-29)NH2(GHRH-Ant). Six healthy young men were given a bolus injection of GHRH-An...

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Pubblicato in:J Clin Invest
Autori principali: Jaffe, C A, Friberg, R D, Barkan, A L
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8349808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116639
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