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Significance of host cell kinases in herpes simplex virus type 1 egress and lamin-associated protein disassembly from the nuclear lamina

The nuclear lamina is thought to be a steric barrier to the herpesvirus capsid. Disruption of the lamina accompanied by phosphorylation of lamina proteins is a conserved feature of herpesvirus infection. In HSV-1-infected cells, protein kinase C (PKC) alpha and delta isoforms are recruited to the nu...

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Main Authors: Leach, Natalie R., Roller, Richard J.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948959/
https://ncbi.nlm.nih.gov/pubmed/20674954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.002
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