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Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus and nucleus accumbens in old rats after chronic donepezil administration

In Alzheimer's disease brains morphological changes in the dendrites of pyramidal neurons of the prefrontal cortex (PFC) and hippocampus have been observed. These changes are particularly reflected in the decrement of both the dendritic tree and spine number. Donepezil is a potent and selective...

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Détails bibliographiques
Auteurs principaux: Alcantara-Gonzalez, Faviola, Juarez, Ismael, Solis, Oscar, Martinez-Tellez, Isaura, Camacho-Abrego, Israel, Masliah, Eliezer, Mena, Raul, Flores, Gonzalo
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948955/
https://ncbi.nlm.nih.gov/pubmed/20336627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20787
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