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Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus and nucleus accumbens in old rats after chronic donepezil administration

In Alzheimer's disease brains morphological changes in the dendrites of pyramidal neurons of the prefrontal cortex (PFC) and hippocampus have been observed. These changes are particularly reflected in the decrement of both the dendritic tree and spine number. Donepezil is a potent and selective...

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Detalhes bibliográficos
Main Authors: Alcantara-Gonzalez, Faviola, Juarez, Ismael, Solis, Oscar, Martinez-Tellez, Isaura, Camacho-Abrego, Israel, Masliah, Eliezer, Mena, Raul, Flores, Gonzalo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948955/
https://ncbi.nlm.nih.gov/pubmed/20336627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20787
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