Human neutrophil-mediated fungistasis against Histoplasma capsulatum. Localization of fungistatic activity to the azurophil granules.

Human neutrophils (PMN) demonstrated potent fungistatic activity against Histoplasma capsulatum (Hc) yeasts in a sensitive microassay that quantifies the growth of yeasts by the incorporation of [3H]leucine. At a PMN:yeast ratio of 1:2, PMN inhibited the growth of yeasts by 37%. Maximum inhibition o...

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Publié dans:	J Clin Invest
Auteurs principaux:	Newman, S L, Gootee, L, Gabay, J E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8349801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116630
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