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Thermosensitive Pluronic(®) hydrogel: prolonged injectable formulation for drug abuse

OBJECTIVE: The main objective of this study was to investigate thermosensitive Pluronic(®) F-127 (PF-127) hydrogel for the modified release of a potent alcohol and opioid antagonist, naltrexone (NTX) hydrochloride, in a subcutaneous injectable dosage form. METHODS: The NTX hydrogels were prepared by...

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Autors principals: Derakhshandeh, Katayoun, Fashi, Mahtab, Seifoleslami, Seyedalireza
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948935/
https://ncbi.nlm.nih.gov/pubmed/20957216
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