Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-Derived ALDH1 Positive Cells

Recent studies suggest that ALDH1 is a putative marker for HNSCC-derived cancer stem cells. However, the regulation mechanisms that maintain the stemness and metastatic capability of HNSCC-ALDH1(+) cells remain unclear. Initially, HNSCC-ALDH1(+) cells from HNSCC patient showed cancer stemness proper...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Cheng-Chia, Lo, Wen-Liang, Chen, Yi-Wei, Huang, Pin-I, Hsu, Han-Shui, Tseng, Ling-Ming, Hung, Shih-Chieh, Kao, Shou-Yen, Chang, Charn-Jung, Chiou, Shih Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948925/
https://ncbi.nlm.nih.gov/pubmed/20936121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/609259
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