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The Tumor Microenvironment and DNA Repair

Genetic instability is one of the hallmarks of cancer cells. As tumors grow, they progressively acquire mutations that ultimately allow them to invade normal tissues and metastasize to distant sites. This increased propensity for mutation also leads to cancers that are resistant to therapeutic inter...

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Autori principali: Klein, Thomas J., Glazer, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948843/
https://ncbi.nlm.nih.gov/pubmed/20832021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2010.05.006
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