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Laminar Shear Stress Modulates Phosphorylation and Localization of RNA Polymerase II on the Endothelial Nitric Oxide Synthase Gene
OBJECTIVE: In endothelial cells exposed to unidirectional, laminar shear stress (LSS), eNOS transcription, mRNA stability, and protein levels are enhanced. We have previously demonstrated that these changes are associated with increased 3′ polyadenylation of eNOS mRNA. Here, we investigated the effe...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948754/ https://ncbi.nlm.nih.gov/pubmed/20167666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.199554 |
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