Human Serum Processing and Analysis Methods for Rapid and Reproducible N-Glycan Mass Profiling

Glycans constitute a new class of compounds for biomarker discovery. Glycosylation is a common post-translational modification and is often associated with transformation to malignancy. To analyze glycans, they are released from proteins, enriched, and measured with mass spectrometry. For biomarker...

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Main Authors: Kronewitter, Scott R., de Leoz, Maria Lorna A., Peacock, Kyle S., McBride, Kelly R., An, Hyun Joo, Miyamoto, Suzanne, Leiserowitz, Gary S., Lebrilla, Carlito B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948646/
https://ncbi.nlm.nih.gov/pubmed/20698584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100202a
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