Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2)

Merozoite surface protein 2 (MSP2) from the human malaria parasite Plasmodium falciparum is expressed as a GPI-anchored protein on the merozoite surface. MSP2 is assumed to have a role in erythrocyte invasion and is a leading vaccine candidate. Recombinant MSP2 forms amyloid-like fibrils upon storag...

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Autores principales: Yang, Xiaodong, Adda, Christopher G., MacRaild, Christopher A., Low, Andrew, Zhang, Xuecheng, Zeng, Weiguang, Jackson, David C., Anders, Robin F., Norton, Raymond S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948610/
https://ncbi.nlm.nih.gov/pubmed/20542076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2010.06.001
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