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Unbiased and Locally Efficient Estimation of Genetic Effect on Quantitative Trait in the Presence of Population Admixture
Population admixture can be a confounding factor in genetic association studies. Family-based methods (Rabinowitz and Laird 2000) have been proposed in both testing and estimation settings to adjust for this confounding, especially in case-only association studies. The family-based methods rely on c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948587/ https://ncbi.nlm.nih.gov/pubmed/20560930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2010.01454.x |
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