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Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

Salivary gland atrophy is a common consequence of pathology, including Sjögren's syndrome, irradiation therapy and obstructive sialadenitis. During severe atrophy of the rat submandibular gland caused by excretory duct ligation, the majority of acinar cells disappear through apoptosis, whereas...

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Bibliografiske detaljer
Main Authors: Silver, N, Proctor, G B, Arno, M, Carpenter, G H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948542/
https://ncbi.nlm.nih.gov/pubmed/20890458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2009.12
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