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Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

Salivary gland atrophy is a common consequence of pathology, including Sjögren's syndrome, irradiation therapy and obstructive sialadenitis. During severe atrophy of the rat submandibular gland caused by excretory duct ligation, the majority of acinar cells disappear through apoptosis, whereas...

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Détails bibliographiques
Auteurs principaux: Silver, N, Proctor, G B, Arno, M, Carpenter, G H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948542/
https://ncbi.nlm.nih.gov/pubmed/20890458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2009.12
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