Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomised controlled trial

BACKGROUND: Herpes simplex virus (HSV) suppressive therapy reduces genital and plasma HIV-1 RNA over periods up to three months but the longer-term effect is unknown. METHODS: 484 HIV-1 and HSV-2 seropositive Tanzanian women aged 16-35 years were enrolled in a randomised placebo-controlled trial of...

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Main Authors: Tanton, Clare, Weiss, Helen A, Rusizoka, Mary, LeGoff, Jerome, Changalucha, John, Baisley, Kathy, Mugeye, Kokugonza, Everett, Dean, Belec, Laurent, Clayton, Tim C., Ross, David A., Hayes, Richard J., Watson-Jones, Deborah
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948536/
https://ncbi.nlm.nih.gov/pubmed/20235836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651696
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