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RNAi Experiments in D. melanogaster: Solutions to the Overlooked Problem of Off-Targets Shared by Independent dsRNAs

BACKGROUND: RNAi technology is widely used to downregulate specific gene products. Investigating the phenotype induced by downregulation of gene products provides essential information about the function of the specific gene of interest. When RNAi is applied in Drosophila melanogaster or Caenorhabdi...

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Bibliografski detalji
Glavni autori: Seinen, Erwin, Burgerhof, Johannes G. M., Jansen, Ritsert C., Sibon, Ody C. M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948504/
https://ncbi.nlm.nih.gov/pubmed/20957038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013119
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