GLP-1 Receptor Stimulation Reduces Amyloid-β Peptide Accumulation and Cytotoxicity in Cellular and Animal Models of Alzheimer’s Disease

Type 2 (T2) diabetes mellitus (DM) has been associated with an increased incidence of neurodegenerative disorders, including Alzheimer’s disease (AD). Several pathological features are shared between diabetes and AD, including dysfunctional insulin signaling and a dysregulation of glucose metabolism...

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Detalhes bibliográficos
Main Authors: Li, Yazhou, Duffy, Kara B., Ottinger, Mary Ann, Ray, Balmiki, Bailey, Jason A., Holloway, Harold W., Tweedie, David, Perry, TracyAnn, Mattson, Mark P., Kapogiannis, Dimitrios, Sambamurti, Kumar, Lahiri, Debomoy K., Greiga, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948479/
https://ncbi.nlm.nih.gov/pubmed/20308787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1314
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