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Structural Determinants of Cadherin-23 Function in Hearing and Deafness
The hair-cell tip link, a fine filament directly conveying force to mechanosensitive transduction channels, is composed of two proteins, protocadherin-15 and cadherin-23, whose mutation causes deafness. However, their molecular structure, elasticity, and deafness-related structural defects are unkno...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948466/ https://ncbi.nlm.nih.gov/pubmed/20399731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.03.028 |
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