Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain

OBJECTIVE: The aim of this study was to assess safety and efficacy of fixed combination oxycodone prolonged release (PR)/naloxone PR in terms of both analgesia and improving opioid-induced bowel dysfunction (OIBD) and associated symptoms, such as opioid-induced constipation (OIC), in adults with chr...

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Bibliographic Details
Main Authors: Sandner-Kiesling, A, Leyendecker, P, Hopp, M, Tarau, L, Lejcko, J, Meissner, W, Sevcik, P, Hakl, M, Hrib, R, Uhl, R, Dürr, H, Reimer, K
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
Subjects:
Non-Cancer Pain
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948431/
https://ncbi.nlm.nih.gov/pubmed/20370845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-1241.2010.02360.x
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