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Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation

The best characterized pathway for the initiation of mRNA degradation in Escherichia coli involves the removal of the 5′-terminal pyrophosphate to generate a monophosphate group that stimulates endonucleolytic cleavage by RNase E. We show here however, using well-characterized oligonucleotide substr...

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Detalhes bibliográficos
Main Authors: Kime, Louise, Jourdan, Stefanie S, Stead, Jonathan A, Hidalgo-Sastre, Ana, McDowall, Kenneth J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948425/
https://ncbi.nlm.nih.gov/pubmed/19889093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06935.x
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