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Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

Pulmonary arterial hypertension (PAH) is usually a devastating condition with a poor prognosis. Nearly 10 years ago, the underlying molecular basis of heritable PAH was elucidated with the identification of mutations in the gene encoding the bone morphogenetic protein type II receptor (BMPR-II). Thi...

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Bibliografske podrobnosti
Glavni avtor: Morrell, Nicholas W
Format: Artigo
Jezik:Inglês
Izdano: Faculty of 1000 Ltd 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948374/
https://ncbi.nlm.nih.gov/pubmed/20948811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-22
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