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Genetics of pulmonary arterial hypertension: do the molecular findings have translational value?

Pulmonary arterial hypertension (PAH) is usually a devastating condition with a poor prognosis. Nearly 10 years ago, the underlying molecular basis of heritable PAH was elucidated with the identification of mutations in the gene encoding the bone morphogenetic protein type II receptor (BMPR-II). Thi...

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Bibliografiske detaljer
Hovedforfatter: Morrell, Nicholas W
Format: Artigo
Sprog:Inglês
Udgivet: Faculty of 1000 Ltd 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948374/
https://ncbi.nlm.nih.gov/pubmed/20948811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-22
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