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Aptamer-based Electrochemical Biosensor for Interferon Gamma Detection

In this paper, we describe the development of an electrochemical DNA aptamer-based biosensor for detection of IFN-γ. A DNA hairpin containing IFN-γ-binding aptamer was thiolated, conjugated with Methylene Blue (MB) redox tag and immobilized on a gold electrode by self-assembly. Binding of IFN-γ caus...

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Main Authors: Liu, Ying, Tuleouva, Nazgul, Ramanculov, Erlan, Revzin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948235/
https://ncbi.nlm.nih.gov/pubmed/20815336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101409t
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