Clostridium perfringens Epsilon Toxin Targets Granule Cells in the Mouse Cerebellum and Stimulates Glutamate Release

Epsilon toxin (ET) produced by C. perfringens types B and D is a highly potent pore-forming toxin. ET-intoxicated animals express severe neurological disorders that are thought to result from the formation of vasogenic brain edemas and indirect neuronal excitotoxicity. The cerebellum is a predilecti...

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Detalhes bibliográficos
Main Authors: Lonchamp, Etienne, Dupont, Jean-Luc, Wioland, Laetitia, Courjaret, Raphaël, Mbebi-Liegeois, Corinne, Jover, Emmanuel, Doussau, Frédéric, Popoff, Michel R., Bossu, Jean-Louis, de Barry, Jean, Poulain, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948003/
https://ncbi.nlm.nih.gov/pubmed/20941361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013046
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