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Brain Mitochondrial Dysfunction in Aging, Neurodegeneration, and Parkinson's Disease

Brain senescence and neurodegeneration occur with a mitochondrial dysfunction characterized by impaired electron transfer and by oxidative damage. Brain mitochondria of old animals show decreased rates of electron transfer in complexes I and IV, decreased membrane potential, increased content of the...

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Detalhes bibliográficos
Main Authors: Navarro, Ana, Boveris, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947925/
https://ncbi.nlm.nih.gov/pubmed/20890446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00034
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