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Role of symmetric and asymmetric division of stem cells in developing drug resistance

Often, resistance to drugs is an obstacle to a successful treatment of cancer. In spite of the importance of the problem, the actual mechanisms that control the evolution of drug resistance are not fully understood. Many attempts to study drug resistance have been made in the mathematical modeling l...

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Библиографические подробности
Главные авторы: Tomasetti, Cristian, Levy, Doron
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947914/
https://ncbi.nlm.nih.gov/pubmed/20826440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007726107
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