Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function

The NSD (nuclear receptor-binding SET domain protein) family encodes methyltransferases that are important in multiple aspects of development and disease. Perturbations in NSD family members can lead to Sotos syndrome and Wolf–Hirschhorn syndrome as well as cancers such as acute myeloid leukemia. Pr...

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Détails bibliographiques
Auteurs principaux: Lucio-Eterovic, Agda Karina, Singh, Melissa M., Gardner, Jeffrey E., Veerappan, Chendhore S., Rice, Judd C., Carpenter, Phillip B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947892/
https://ncbi.nlm.nih.gov/pubmed/20837538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002653107
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