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ADAR1 RNA Deaminase Limits Short Interfering RNA Efficacy in Mammalian Cells
Double-stranded RNA induces the homology-dependent degradation of cognate mRNA in the cytoplasm via RNA interference (RNAi) but also is a target for adenosine-to-inosine (A-to-I) RNA editing by adenosine deaminases acting on RNA (ADARs). An interaction between the RNAi and the RNA editing pathways i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947832/ https://ncbi.nlm.nih.gov/pubmed/15556947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M407876200 |
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