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Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

Shugoshin (Sgo) is a conserved centromeric protein. Mammalian Sgo1 collaborates with protein phosphatase 2A (PP2A) to protect mitotic cohesin from the prophase dissociation pathway. Although another shugoshin-like protein, Sgo2, is required for the centromeric protection of cohesion in germ cells, i...

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Detalhes bibliográficos
Main Authors: Tanno, Yuji, Kitajima, Tomoya S., Honda, Takashi, Ando, Yasuto, Ishiguro, Kei-ichiro, Watanabe, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947769/
https://ncbi.nlm.nih.gov/pubmed/20889715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1945310
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