FGF8 acts as a classic diffusible morphogen to pattern the neocortex

Gain- and loss-of-function experiments have demonstrated that a source of fibroblast growth factor (FGF) 8 regulates anterior to posterior (A/P) patterning in the neocortical area map. Whether FGF8 controls patterning as a classic diffusible morphogen has not been directly tested. We report evidence...

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Detalles Bibliográficos
Main Authors: Toyoda, Reiko, Assimacopoulos, Stavroula, Wilcoxon, Jennifer, Taylor, Albert, Feldman, Polina, Suzuki-Hirano, Asuka, Shimogori, Tomomi, Grove, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2010
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947756/
https://ncbi.nlm.nih.gov/pubmed/20843859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055392
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