Quantitative Phosphoproteomics of Proteasome Inhibition in Multiple Myeloma Cells

BACKGROUND: The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of cytotoxicity is not well understood. METHODO...

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Detalhes bibliográficos
Main Authors: Ge, Feng, Xiao, Chuan-Le, Bi, Li-Jun, Tao, Sheng-Ce, Xiong, Sheng, Yin, Xin-Feng, Li, Li-Ping, Lu, Chun-Hua, Jia, Hai-Tao, He, Qing-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947515/
https://ncbi.nlm.nih.gov/pubmed/20927383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013095
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