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Fibrin Degradation Enhances Vascular Smooth Muscle Cell Proliferation and Matrix Deposition in Fibrin-Based Tissue Constructs Fabricated In Vitro

Completely biological tissue replacements can be fabricated by entrapping cells in a molded fibrin gel. Over time, the fibrin is degraded and replaced with cell-produced extracellular matrix. However, the relationship between fibrin degradation and matrix deposition has not been elucidated. We devel...

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Détails bibliographiques
Auteurs principaux: Ahmann, Katherine A., Weinbaum, Justin S., Johnson, Sandra L., Tranquillo, Robert T.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947425/
https://ncbi.nlm.nih.gov/pubmed/20536358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2009.0708
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