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Validation of the high-dose heparin confirmatory step for the diagnosis of heparin-induced thrombocytopenia

The diagnosis of heparin-induced thrombocytopenia (HIT) requires detection of antibodies to the heparin/platelet factor 4 (PF4) complexes via enzyme-linked immunosorbent assay. Addition of excess heparin to the sample decreases the optical density by 50% or more and confirms the presence of these an...

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Autori principali: Whitlatch, Nicole L., Kong, David F., Metjian, Ara D., Arepally, Gowthami M., Ortel, Thomas L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947396/
https://ncbi.nlm.nih.gov/pubmed/20508160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-262659
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