Trophoblast- and Vascular Smooth Muscle Cell-Derived MMP-12 Mediates Elastolysis during Uterine Spiral Artery Remodeling

During the first trimester of pregnancy, the uterine spiral arteries are remodeled, creating heavily dilated conduits that lack maternal vasomotor control but allow the placenta to meet an increasing requirement for nutrients and oxygen. To effect permanent vasodilatation, the internal elastic lamin...

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Detalhes bibliográficos
Main Authors: Harris, Lynda K., Smith, Samantha D., Keogh, Rosemary J., Jones, Rebecca L., Baker, Philip N., Knöfler, Martin, Cartwright, Judith E., Whitley, Guy St. J., Aplin, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947303/
https://ncbi.nlm.nih.gov/pubmed/20802175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100182
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