Blockade of Endothelin-1 with a Novel Series of 1,3,6-Trisubstituted-2-Carboxy-Quinol-4-Ones Controls Infection-Associated Preterm Birth

Preterm birth (PTB) currently accounts for 13% of all births in the United States, with the leading cause of PTB being maternal infection. Endothelin-1, an extremely potent vasoconstrictor capable of increasing myometrial smooth muscle tone, has been shown to be up-regulated in the setting of infect...

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Bibliographic Details
Main Authors: Olgun, Nicole S., Patel, Hardik J., Stephani, Ralph, Lengyel, Istvan, Reznik, Sandra E.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947287/
https://ncbi.nlm.nih.gov/pubmed/20802183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100281
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