Alveolar Macrophages Stimulate Enhanced Cytokine Production by Pulmonary CD4(+) T-Lymphocytes in an Exacerbation of Murine Chronic Asthma

The mechanisms underlying the exaggerated distal airway inflammation and hyperresponsiveness that characterize acute exacerbations of asthma are largely unknown. Using BALB/c mouse experimental models, we demonstrated a potentially important role for alveolar macrophages (AM) in the development of a...

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Detalhes bibliográficos
Main Authors: Herbert, Cristan, Scott, Melissa M., Scruton, Kim H., Keogh, Rylie P., Yuan, Kristy C., Hsu, Kenneth, Siegle, Jessica S., Tedla, Nicodemus, Foster, Paul S., Kumar, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947263/
https://ncbi.nlm.nih.gov/pubmed/20724599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100019
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