Defective migration of neuroendocrine GnRH cells in human arrhinencephalic conditions

Patients with Kallmann syndrome (KS) have hypogonadotropic hypogonadism caused by a deficiency of gonadotropin-releasing hormone (GnRH) and a defective sense of smell related to olfactory bulb aplasia. Based on the findings in a fetus affected by the X chromosome–linked form of the disease, it has b...

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Autores principales: Teixeira, Luis, Guimiot, Fabien, Dodé, Catherine, Fallet-Bianco, Catherine, Millar, Robert P., Delezoide, Anne-Lise, Hardelin, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2010
Materias:
Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947242/
https://ncbi.nlm.nih.gov/pubmed/20940512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43699
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