Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation

Cardiac valve formation is crucial for embryonic and adult heart function. Valve malformations constitute the most common congenital cardiac defect, but little is known about the molecular mechanisms regulating valve formation and homeostasis. Here, we show that endocardial Notch1 and myocardial Bmp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Luna-Zurita, Luis, Prados, Belén, Grego-Bessa, Joaquim, Luxán, Guillermo, del Monte, Gonzalo, Benguría, Alberto, Adams, Ralf H., Pérez-Pomares, José María, de la Pompa, José Luis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947227/
https://ncbi.nlm.nih.gov/pubmed/20890042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42666
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars