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Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation

Aging leads to the disruption of the homeostatic balance of multiple biological systems. In bone marrow multipotent mesenchymal cells undergo differentiation into various anchorage-dependent cell types, including osteoblasts and adipocytes. With age as well as with treatment of antidiabetic drugs su...

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Hlavní autoři: Nishikawa, Keizo, Nakashima, Tomoki, Takeda, Shu, Isogai, Masashi, Hamada, Michito, Kimura, Ayako, Kodama, Tatsuhiko, Yamaguchi, Akira, Owen, Michael J., Takahashi, Satoru, Takayanagi, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947225/
https://ncbi.nlm.nih.gov/pubmed/20877012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42528
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