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The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein

In mammalian cells, MCTs (monocarboxylate transporters) require association with an ancillary protein to enable plasma membrane expression of the active transporter. Basigin is the preferred binding partner for MCT1, MCT3 and MCT4, and embigin for MCT2. In rat and rabbit erythrocytes, MCT1 is associ...

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Bibliografische gegevens
Hoofdauteurs: Ovens, Matthew J., Manoharan, Christine, Wilson, Marieangela C., Murray, Clarey M., Halestrap, Andrew P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947196/
https://ncbi.nlm.nih.gov/pubmed/20695846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100890
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