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Cyclothiazide induces seizure behavior in freely moving rats

We have previously demonstrated that cyclothiazide (CTZ) is a potent convulsant drug inducing robust epileptiform activity in hippocampal neurons both in vitro and in vivo. Here we further establish an animal model for CTZ-induced behavioral seizures in freely moving rats. Microinjection of CTZ into...

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Detalhes bibliográficos
Main Authors: Kong, Shuzhen, Qian, Binbin, Liu, Jianhui, Fan, Mingxin, Chen, Gong, Wang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947190/
https://ncbi.nlm.nih.gov/pubmed/20678492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.07.088
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