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Leishmania-Specific Surface Antigens Show Sub-Genus Sequence Variation and Immune Recognition

BACKGROUND: A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in t...

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Détails bibliographiques
Auteurs principaux: Depledge, Daniel P., MacLean, Lorna M., Hodgkinson, Michael R., Smith, Barbara A., Jackson, Andrew P., Ma, Saufung, Uliana, Silvia R. B., Smith, Deborah F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946902/
https://ncbi.nlm.nih.gov/pubmed/20927190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000829
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