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Leishmania-Specific Surface Antigens Show Sub-Genus Sequence Variation and Immune Recognition

BACKGROUND: A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in t...

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Detalhes bibliográficos
Main Authors: Depledge, Daniel P., MacLean, Lorna M., Hodgkinson, Michael R., Smith, Barbara A., Jackson, Andrew P., Ma, Saufung, Uliana, Silvia R. B., Smith, Deborah F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946902/
https://ncbi.nlm.nih.gov/pubmed/20927190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000829
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