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Inhibition of NR2B Phosphorylation Restores Alterations in NMDA Receptor Expression and Improves Functional Recovery following Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) triggers a massive glutamate efflux, hyperactivation of N-methyl-d-aspartate receptors (NMDARs) and neuronal cell death. Previously it was demonstrated that, 15 min following experimentally induced closed head injury (CHI), the density of activated NMDARs increases in th...

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Autori principali: Schumann, Johanna, Alexandrovich, G. Alexander, Biegon, Anat, Yaka, Rami
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946870/
https://ncbi.nlm.nih.gov/pubmed/18721106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0521
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